OLM 11.3. Genetic drift and inbreeding


The genetic differentiation of small populations is often characterized by Wright’s F statistics, because inbreeding depression depends on the increasing probability of two alleles identical by descent to come together in the same individual due to the homogenizing effect of genetic drift. We introduce the concept of the coefficient of inbreeding in this OLM, we show how it increases generation by generation in a population of finite size, and connect it to the variance of allele frequencies discussed in OLM 11.1.


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